Understand possible side effects

Side Effects

It’s important to understand the possible side effects you may experience when taking INTELENCE® (etravirine) with other HIV medicines. While many side effects can be managed, some are more serious than others.

INTELENCE® side effects

  • Skin rash is a common side effect of INTELENCE®. The risk of getting a skin rash is higher in females. Rarely, rash can be severe and may lead to death. Severe skin rash with blisters or peeling skin, including the area around the mouth or eyes, may happen more frequently in children less than 18 years of age who take INTELENCE® in combination with other HIV-1 medicines than in adults. Call your healthcare provider right away if a rash develops; severe cases may need to be treated in a hospital.
  • If you get a rash with any of the following symptoms, stop taking INTELENCE® and call your healthcare provider or get medical help right away:
    • Fever
    • Generally ill feeling
    • Extreme tiredness
    • Muscle or joint aches
    • Blisters or sores in mouth
    • Blisters or peeling of the skin
    • Redness or swelling of the eyes
    • Swelling of the mouth, lips, or face
    • Problems breathing
  • As with other HIV medicines, INTELENCE® may cause side effects, including:
    • Immune reconstitution syndrome. Signs and symptoms of inflammation from opportunistic infections that a person has or had may occur as the medicines work to control the HIV infection and strengthen the immune system. Call your healthcare provider right away if you experience any signs or symptoms of an infection
    • Changes in body shape or body fat. The cause and long-term health effects of these conditions are not known at this time
  • Other common side effects of INTELENCE® include tingling or pain in hands or feet, and numbness
  • Other side effects of INTELENCE®, which can be serious, include muscle pain, tenderness or weakness

This is not a complete list of all side effects. If you experience these or other symptoms, contact your healthcare provider right away. Do not stop taking INTELENCE® or any other medications without first talking to your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see additional Important Safety Information below.

Important Safety Information